Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interaction between smoking and PON2 Ser311Cys polymorphism as a determinant of the risk of myocardial infarction.

European journal of clinical investigation - 1 Jan 2004

Martinelli N, Girelli D, Olivieri O, Stranieri C, Trabetti E, Pizzolo F, Friso S, Tenuti I, Cheng S, Grow M A, Pignatti P F, Corrocher R

Abstract excerpt

BACKGROUND: Increased oxidative stress is thought to play a role in the pathogenesis of the atherothrombotic process. Paraoxonases (PONs) are closely related antioxidant enzymes encoded by clustered genes on chromosome 7q. We evaluated three PON polymorphisms (PON1 Leu55Met and Gln192Arg; PON2 Ser311Cys) as possible risk factors for coronary atherosclerotic disease (CAD) and/or its main thrombotic complication,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aryldialkylphosphatase
Share to Coronary Artery Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Malondialdehyde

Share to Myocardial Infarction

Share to Oxidative Stress

Share to Polymorphism, Genetic

Share to Risk Factors

Share to Smoking

Source

Identifiers

PMID: 14984433
DOI: 10.1111/j.1365-2362.2004.01292.x

Genes

PON2
CAD
PON1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interaction between smoking and PON2 Ser311Cys polymorphism as a determinant of the risk of myocardial infarction.PMID 14984433Read ↗

Paraoxonase 2 C311S single nucleotide polymorphism is associated with type C lesions in coronary atherosclerosis.Semantic proximity Read ↗

Relationship between rs854560 PON1 Gene Polymorphism and Tobacco Smoking with Coronary Artery Disease.Semantic proximity Read ↗

Association Between Paraoxonase 2 Ser311Cys Polymorphism and Coronary Heart Disease Risk: A Meta-Analysis.Semantic proximity Read ↗

Paraoxonase 1 L55M, Q192R and paraoxonase 2 S311C alleles in atherothrombosis.Semantic proximity Read ↗

Interaction effects between Paraoxonase 1 variants and cigarette smoking on risk of coronary heart disease in a Singaporean Chinese population.Semantic proximity Read ↗

Impact of inflammation, gene variants, and cigarette smoking on coronary artery disease risk.Semantic proximity Read ↗

The role of polymorphisms within paraoxonases (192 Gln/Arg in PON1 and 311Ser/Cys in PON2) in the modulation of cardiovascular risk: a pilot study.Semantic proximity Read ↗

Synergistic effects between Q192R polymorphism of paraoxonase 1 gene and some conventional risk factors in premature coronary artery disease.Semantic proximity Read ↗

Tobacco smoking modifies association between Gln-Arg192 polymorphism of human paraoxonase gene and risk of myocardial infarction.Semantic proximity Read ↗

Differential effects of smoking on myocardial infarction risk according to the Gln/Arg 192 variants of the human paraoxonase gene.Semantic proximity Read ↗

Paraoxonase2 C311S polymorphism and low levels of HDL contribute to a higher mortality risk after acute myocardial infarction in elderly patients.Semantic proximity Read ↗

Association between paraoxonase 2 Ser311Cys polymorphism and ischemic stroke risk: a meta-analysis involving 5,008 subjects.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.