Article
Disseminated diffuse midline glioma associated with poorly differentiated orbital lesion and metastases in an 8-year-old girl: case report and literature review.
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery - 1 Oct 2022
Silva Michael A, Mirchia Kanish, Chamyan Gabriel, Maher Ossama, Wang Shelly, Niazi Toba
Abstract excerpt
BACKGROUND: Disseminated diffuse midline glioma (DMG) is a devastating diagnosis. Molecular subtyping has increased our understanding of this tumor. CASE: Here, we report the case of an 8-year-old girl who presented with symptoms of brainstem dysfunction and was found to have disseminated DMG with lesions in the pons, thalamus and bilateral temporal lobes. Molecular subtyping of the temporal lobe tumor tissue was...
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