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Article

Type 1 diabetes: current concepts in epidemiology, pathophysiology, clinical care, and research.

Current problems in pediatric and adolescent health care - 1 Jan 2000

Gan Mary Joyce, Albanese-O'Neill Anastasia, Haller Michael J

Abstract excerpt

Type 1 diabetes (T1D) is an autoimmune disease mediated by a combination of genetic and environmental triggers resulting in lymphocytic infiltration of pancreatic islets, destruction of beta cells, and lifelong dependency on exogenous insulin. Although T1D is prevalent (1 in 300) and its incidence is steadily increasing worldwide (3% per year), the exact gene-environment interactions precipitating the disease...

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Identifiers

PMID: 23046732
DOI: 10.1016/j.cppeds.2012.07.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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