Article
The genetic variation of SORCS1 is associated with late-onset Alzheimer's disease in Chinese Han population.
PloS one - 1 Jan 2013
Xu Wei, Xu Jun, Wang Ying, Tang Huidong, Deng Yulei, Ren Rujing, Wang Gang, Niu Wenquan, Ma Jianfang, Wu Yiwen, Zheng Jialin, Chen Shengdi, Ding Jianqing
Abstract excerpt
The variations of SORCS1 gene may play potential key roles in late-onset Alzheimer's disease (LOAD). To evaluate the relationship between the polymorphism of SORCS1 gene and LOAD in the ethnic Han Chinese, we conducted a case-control study to investigate the association between the single-nucleotide polymorphisms (SNPs) in intron 1 of SORCS1 and LOAD in Chinese Han population. Six reported SNPs in intron 1 of...
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