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ZEB1 serves as an oncogene in acute myeloid leukaemia via regulating the PTEN/PI3K/AKT signalling pathway by combining with P53

7 May 2021

Abstract excerpt

Acute myeloid leukaemia is a complex, highly aggressive hematopoietic disorder. Currently, in spite of great advances in radiotherapy and chemotherapy, the prognosis for AML patients with initial treatment failure is still poor. Therefore, the need for novel and efficient therapies to improve AML treatment outcome has become desperately urgent. In this study, we identified the expression of ZEB1 (a transcription...

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Acute Myeloid Leukemia Research
Histone Deacetylase Inhibitors Research
Myeloproliferative Neoplasms: Diagnosis and Treatment

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33960640
DOI: 10.1111/jcmm.16539

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