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Article

Association between genetic variations of mitochondrial isocitrate dehydrogenase (IDH2) and acute myocardial infarction.

Gene - 30 Jun 2022

Watany Mona M, Nagi Abd-Ellatif Rania, Ezzelregal Abdeldayem Mohamed, El-Sayed El-Horany Hemat

Abstract excerpt

PURPOSE: Mitochondrial isocitrate dehydrogenase (IDH2) is a major contributor to cellular redox control. The aim of this study was to preliminary link IDH2 genetic variations to redox imbalance, atherogenesis and risk of acute myocardial infarction (AMI). METHODS: This case-control study included 120 AMI patients and 120 healthy controls. IDH2 genetic variations were tested using direct sequencing. IDH2 enzyme...

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Identifiers

PMID: 35447240
DOI: 10.1016/j.gene.2022.146497

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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