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Article

A clinical study of genetic testing to guide the dosing of warfarin after heart valve replacement.

BMC cardiovascular disorders - 19 Apr 2022

Zhang Fan, Zhang Congcong, Gu Chengxiong, Yu Yang, Li Jingxing

Abstract excerpt

OBJECTIVE: To explore the role of genetic testing of VKORC1 and CYP2C9 in determining the dosage of warfarin after aortic valve replacement. METHODS: A total of 172 patients receiving warfarin after aortic valve replacement were divided into a control group (n = 86) and an experimental (n = 86) group based on acceptance of genetic testing. In the experimental group, three loci of VKORC1 and CYP2C9 were tested by...

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Identifiers

PMID: 35439929
DOI: 10.1186/s12872-022-02620-x
PMCID: PMC9019963

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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