Article
Genotype-guided warfarin dosing may benefit patients with mechanical aortic valve replacements: randomized controlled study.
Scientific reports - 24 Apr 2020
Lee Kyung Eun, Yee Jeong, Lee Gwan Yung, Chung Jee Eun, Seong Jong Mi, Chang Byung Chul, Gwak Hye Sun
Abstract excerpt
This prospective, single-blind, randomized study was designed to evaluate the effect of genotype-based warfarin dosing compared with standard warfarin dosing in Korean patients with mechanical cardiac valves. Patients were assigned to either the genotype-based dosing group or the standard dosing group using stratified block randomization. The genotype-based dosing equation was adopted from a previous study which...
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