Article

Detection of Inherited Mutations in Brazilian Breast Cancer Patients Using Multi-Gene panel Testing

2021-07-30

Abstract excerpt

Genetic diversity of germline variants in breast cancer (BC) predisposition genes, is unexplored in miscegenated people, such as Latin American populations. We evaluated 1,662 Brazilian BC patients, who underwent hereditary multi-gene panel testing (20–38 cancer susceptibility genes), to determine the spectrum and prevalence of (likely) pathogenic variants (P/LP) and variants of uncertain significance (VUS). In to...

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Literature Corpus work: 8e07121f-9e2c-5a7e-b991-792650bc6fce
DOI: 10.21203/rs.3.rs-753679/v1

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