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Multigene germline testing usefulness instead of BRCA1/2 single screening in triple negative breast cancer cases.

Pathology, research and practice - 1 Jul 2023

Arranz-Ledo M, Lastra E, Abella L, Ferreira R, Orozco M, Hernández L, Martínez N, Infante M, Durán M

Abstract excerpt

Triple negative breast cancer is considered as the worst aggressive subtype with poor prognosis. Recent studies suggest a hereditary component is involved in TNBC development, especially in young patients. However, genetic spectrum remains unclear. Our purpose was to evaluate the usefulness of multigene panel testing in triple negative patients compared to overall breast cancer cases as well as contributing to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37201465
DOI: 10.1016/j.prp.2023.154514

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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