Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Differential Expression of CD47 may be Related to the Pathogenesis From Myelodysplastic Syndromes to Acute Myeloid Leukemia

31 Mar 2022

Abstract excerpt

Myelodysplastic syndrome (MDS) can lead to the development of peripheral blood cytopenia and abnormal cell morphology. MDS has the potential to evolve into AML and can lead to reduced survival. CD47, a member of the immunoglobulin family, is one molecule that is overexpressed in a variety of cancer cells and is associated with clinical features and poor prognosis in a variety of malignancies. In this study, we...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Myeloid Leukemia Research
Share to Erythrocyte Function and Pathophysiology
Share to Phagocytosis and Immune Regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35433462
DOI: 10.3389/fonc.2022.872999

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Differential Expression of CD47 may be Related to the Pathogenesis From Myelodysplastic Syndromes to Acute Myeloid LeukemiaPMID 35433462Read ↗

CD47 expression in acute myeloid leukemia varies according to genotypeSemantic proximity Read ↗

Advances in Anti-Tumor Treatments Targeting the CD47/SIRPα AxisSemantic proximity Read ↗

Recent Advances of Tumor Therapy Based on the CD47-SIRPα AxisSemantic proximity Read ↗

Role of CD47 in tumor immunity: a potential target for combination therapySemantic proximity Read ↗

The CD47-SIRP signalling system: its physiological roles and therapeutic applicationSemantic proximity Read ↗

CD47 is correlated with immune infiltration and is a prognostic biomarker in colorectal cancerSemantic proximity Read ↗

Isoform switching of CD47 induces macrophage-initiated cancer cell pyroptosisSemantic proximity Read ↗

Engulfment of hematopoietic stem cells caused by down-regulation of CD47 is critical in the pathogenesis of hemophagocytic lymphohistiocytosis.Semantic proximity Read ↗

SIRPα controls CD47-dependent platelet clearance in mice and humansSemantic proximity Read ↗

A Perspective on the CD47-SIRPA Axis in High-Risk NeuroblastomaSemantic proximity Read ↗

HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cellsSemantic proximity Read ↗

Disruption of SIRPα signaling in macrophages eliminates human acute myeloid leukemia stem cells in xenograftsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.