Article
Candidate genetic variants and antidepressant-related fall risk in middle-aged and older adults.
PloS one - 1 Jan 2022
Pronk A C, Seppala L J, Trajanoska K, Stringa N, van de Loo B, de Groot L C P G M, van Schoor N M, Koskeridis F, Markozannes G, Ntzani E, Uitterlinden A G, Rivadeneira F, Stricker B H, van der Velde N
Abstract excerpt
BACKGROUND: Antidepressant use has been associated with increased fall risk. Antidepressant-related adverse drug reactions (e.g. orthostatic hypotension) depend partly on genetic variation. We hypothesized that candidate genetic polymorphisms are associated with fall risk in older antidepressant users. METHODS: The association between antidepressant use and falls was cross-sectionally investigated in a cohort of...
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