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Article

Influence of genetic polymorphisms in homocysteine and lipid metabolism systems on antidepressant drug response.

BMC psychiatry - 14 Aug 2020

Yuan Baoyu, Sun Xiaoyan, Xu Zhi, Pu Mengjia, Yuan Yonggui, Zhang Zhijun

Abstract excerpt

BACKGROUND: Variation in genes implicated in homocysteine and lipid metabolism systems may influence antidepressant response for patients with major depressive disorder (MDD). This study aimed to investigate whether association of polymorphisms on the MTHFR, ApoE and ApoA4 genes with the treatment response in MDD subjects. METHODS: A total of 281 Han Chinese MDD patients received a single antidepressant drug...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32795354
DOI: 10.1186/s12888-020-02798-4
PMCID: PMC7427977

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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