Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[The Mutated Gene Sequenced by NGS and the Correlation of Their Coexistent Mutual Exclusiveness in NPM1 Mutated Acute Myeloid Leukemia].

Zhongguo shi yan xue ye xue za zhi - 1 Dec 2021

Dai Li, Wang Zhi-Lin, Qiu Guo-Qiang, Wu Yi-Cun, Zhang Xiu-Wen, Xing Shan-Shan, Wang Biao

Abstract excerpt

OBJECTIVE: To analyze the clinicobiological heterogeneity of NPM1 mutated (NPM1mut) acute myeloid leukemia (AML) detected by next generation sequencing (NGS) and their coexistence and mutual exclusivity relationship in the AML subtype. METHODS: The NGS data based on 112 genes related to blood disease in 238 newly diagnosed patients with NPM1mut were collected. The χ2 test and non-parametric test were used to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to High-Throughput Nucleotide Sequencing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Leukemia, Myeloid, Acute

Share to Mutation

Share to Nuclear Proteins

Source

Identifiers

PMID: 34893102
DOI: 10.19746/j.cnki.issn.1009-2137.2021.06.007

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[The Mutated Gene Sequenced by NGS and the Correlation of Their Coexistent Mutual Exclusiveness in NPM1 Mutated Acute Myeloid Leukemia].PMID 34893102Read ↗

[Coexisting mutations in NPM1-mutated elderly adults with acute myeloid leukemia].Semantic proximity Read ↗

Co-mutation landscape and its prognostic impact on newly diagnosed adult patients with NPM1-mutated de novo acute myeloid leukemiaSemantic proximity Read ↗

[Analysis of Coexisting Gene with NRAS in Acute Myeloid Leukemia].Semantic proximity Read ↗

Only FLT3-ITD co-mutation did not have a deleterious effect on acute myeloid leukemia patients with NPM1 mutation, but concomitant with DNMT3A co-mutation or a < 3log reduction of MRD2 predicted poor survival.Semantic proximity Read ↗

Overlapping features of therapy-related and de novo NPM1-mutated AML.Semantic proximity Read ↗

[Association of Next Generation Sequencing Based Genotypic Profiling with MICM Characteristics in NPM1 Mutated Acute Myeloid Leukemia].Semantic proximity Read ↗

[The immunophenotypic and clinical characteristics of NPM1 mutated acute myeloid leukemia patients].Semantic proximity Read ↗

Coexisting and cooperating mutations in NPM1-mutated acute myeloid leukemia.Semantic proximity Read ↗

Mutational landscape of patients with acute myeloid leukemia or myelodysplastic syndromes in the context of RUNX1 mutation.Semantic proximity Read ↗

The correlation of next-generation sequencing-based genotypic profiles with clinicopathologic characteristics in NPM1-mutated acute myeloid leukemia.Semantic proximity Read ↗

Frequency and Impact of Somatic Co-occurring Mutations on Post-Transplant Outcomes in Acute Myeloid Leukemia: A Multicenter Registry Analysis on Behalf of the EBMT ALWPSemantic proximity Read ↗

[Clinical characteristics of newly diagnosed acute myeloid leukemia patients with NPM1 mutation].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.