Effects of Vitamin D and Body Mass Index on Disease Risk and Relapse Hazard in Multiple Sclerosis: A Mendelian Randomization Study.

Abstract excerpt

BACKGROUND AND OBJECTIVES: Decreased vitamin D levels and obesity are associated with an increased risk for multiple sclerosis (MS). However, whether they also affect the disease course after onset remains unclear. With larger data sets now available, we used Mendelian randomization (MR) to determine whether serum 25-hydroxyvitamin D (25OHD) and body mass index (BMI) are causally associated with MS risk and,...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Body Mass Index
• Share to Genome-Wide Association Study