Article

Apolipoprotein C1 as a Novel Biomarker for Evaluating Immunotherapy Drug Responses and Clinical Prognosis for Microsatellite Unstable Colorectal Cancer

2022-07-18

Abstract excerpt

<h4>Background: </h4> Colorectal cancer (CRC) is the third most common cancer in men and women worldwide. Although improved screening has significantly reduced its incidence, the occurrence and death rates of CRC in younger people have increased in the last few decades. Following initial successes in melanoma treatment, immunotherapy has rapidly become a major treatment modality for deficient mismatch repair/micro...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 8f53dc81-143f-5862-aae4-21cf645c25a4
DOI: 10.21203/rs.3.rs-1827558/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Apolipoprotein C1 as a Novel Biomarker for Evaluating Immunotherapy Drug Responses and Clinical Prognosis for Microsatellite Unstable Colorectal CancerDOI 10.21203/rs.3.rs-1827558/v1Read

Microsatellite Phenotype as a Guide for Immunotherapy in Colorectal Cancer: Current Status and Future Perspectives.Semantic proximity Read

The next bastion to be conquered in immunotherapy: microsatellite stable colorectal cancerSemantic proximity Read

CRC genome-driven metabolic reprogramming and immune microenvironment remodelingSemantic proximity Read

Crosstalk Between the MSI Status and Tumor Microenvironment in Colorectal Cancer.Semantic proximity Read

A Mutational Signature that Predicts Prognosis and Benefit of Immune Checkpoint Blockade in Colorectal CancerSemantic proximity Read

Gene mutation profiling in microsatellite instability colorectal cancer and its association with the efficacy of immunotherapy: A retrospective study.Semantic proximity Read

Beyond Microsatellite Instability: Evolving Strategies Integrating Immunotherapy for Microsatellite Stable Colorectal CancerSemantic proximity Read

Is There a Role for Programmed Death Ligand-1 Testing and Immunotherapy in Colorectal Cancer With Microsatellite Instability? Part I-Colorectal Cancer: Microsatellite Instability, Testing, and Clinical Implications.Semantic proximity Read

Single-cell technology reveals the crosstalk between tumor cells and immune cells: driving immune signal transduction and inflammation-mediated cardiac dysfunction in the tumor microenvironment of colorectal cancerSemantic proximity Read

Tumor Infiltrating Lymphocytes and Macrophages Improve Survival in Microsatellite Unstable Colorectal CancerSemantic proximity Read

Evaluating the Value of Genomic and Immune Features for Survival Prediction Beyond MSI in Colorectal CancerSemantic proximity Read

Predictive molecular markers for the treatment with immune checkpoint inhibitors in colorectal cancerSemantic proximity Read