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Article

Genetic Variants of the BAFF Gene and Risk of Fatigue Among Patients With Primary Sjögren's Syndrome.

Frontiers in immunology - 1 Jan 2022

Flessa Christina-Maria, Zampeli Evangelia, Evangelopoulos Maria-Eleftheria, Natsis Vasilis, Bodewes Iris L A, Huijser Erika, Versnel Marjan A, Moutsopoulos Haralampos M, Mavragani Clio P

Abstract excerpt

Background/Purpose: Primary Sjögren's Syndrome (SS) is characterized by B lymphocyte hyperactivity with B cell activating factor (BAFF) acting as an important regulator. Single Nucleotide Polymorphisms (SNPs) of the BAFF gene have been implicated in the pathogenesis of several autoimmune diseases characterized by heightened fatigue levels, including primary SS. We aimed to explore potential associations between...

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Identifiers

PMID: 35371038
DOI: 10.3389/fimmu.2022.836824
PMCID: PMC8964489

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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