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Article

Epigenome-wide DNA methylation patterns associated with fatigue in primary Sjögren’s syndrome

10 Mar 2016

Abstract excerpt

OBJECTIVE: Chronic fatigue is a common, disabling and poorly understood phenomenon. Recent studies indicate that epigenetic mechanisms may be involved in the expression of fatigue, a prominent feature of primary SS (pSS). The aim of this study was to investigate whether DNA methylation profiles of whole blood are associated with fatigue in patients with pSS. METHODS: Forty-eight pSS patients with high (n = 24) or...

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Cancer survivorship and care
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Salivary Gland Disorders and Functions

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PMID: 26966136
DOI: 10.1093/rheumatology/kew008

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