Article
B-cell activating factor genetic variants in lymphomagenesis associated with primary Sjogren's syndrome.
Journal of autoimmunity - 1 Jun 2014
Nezos Adrianos, Papageorgiou Aristea, Fragoulis George, Ioakeimidis Dimitrios, Koutsilieris Michael, Tzioufas Athanasios G, Moutsopoulos Haralampos M, Voulgarelis Michael, Mavragani Clio P
Abstract excerpt
Primary Sjogren's syndrome (pSS) is complicated by B-cell lymphoma in 5-10% of patients. Several clinical and serological features are proposed as adverse predictors for such complication and define a high risk pSS phenotype. We aimed to explore whether previously described polymorphisms of the B-cell activating factor (BAFF) could be related to pSS-related lymphomagenesis. Five single nucleotide polymorphisms...
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