Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

B cells in the pathogenesis of primary Sjögren syndrome.

Nature reviews. Rheumatology - 1 Mar 2018

Nocturne Gaëtane, Mariette Xavier

Abstract excerpt

Primary Sjögren syndrome (pSS) is a prototypical autoimmune disease. The involvement of B cells in the pathogenesis of pSS has long been suspected on the basis of clinical observations that include the presence of serum autoantibodies, hypergammaglobulinaemia, increased levels of free light chains and increased risk of B cell lymphoma. Moreover, the composition of the B cell subset is altered in pSS. In this...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to B-Cell Activating Factor
Share to B-Lymphocytes
Share to Epigenesis, Genetic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to TNF gene

Share to Genetic Predisposition to Disease

Share to Genome-Wide Association Study

Share to Lymphocyte Activation

Share to Sjogren's Syndrome

Source

Identifiers

PMID: 29416129
DOI: 10.1038/nrrheum.2018.1

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

B cells in the pathogenesis of primary Sjögren syndrome.PMID 29416129Read ↗

Current views on the pathogenesis of Sjögren's syndrome.Semantic proximity Read ↗

Sjögren's syndrome: one year in review 2022Semantic proximity Read ↗

Sjögren's syndrome: one year in review 2023Semantic proximity Read ↗

Recent advances in primary Sjogren's syndromeSemantic proximity Read ↗

A comprehensive review of autoantibodies in primary Sjögren's syndrome: clinical phenotypes and regulatory mechanisms.Semantic proximity Read ↗

[Pathophysiological aspects of primary Sjögren's disease : From epithelial activation to systemic autoimmunity].Semantic proximity Read ↗

Update on Pathogenesis of Sjogren's SyndromeSemantic proximity Read ↗

Primary Sjögren's syndrome: clinical phenotypes, outcome and the development of biomarkers.Semantic proximity Read ↗

Sjögren's syndrome--a plethora of clinical and immunological phenotypes with a complex genetic background.Semantic proximity Read ↗

Contributions of Major Cell Populations to Sjögren’s SyndromeSemantic proximity Read ↗

JAK/STAT pathway targeting in primary Sjögren syndromeSemantic proximity Read ↗

CD8+ T Lymphocytes: Crucial Players in Sjögren's Syndrome.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.