Article
Hepatic adropin is regulated by estrogen and contributes to adverse metabolic phenotypes in ovariectomized mice.
Molecular metabolism - 1 Jun 2022
Stokar Joshua, Gurt Irina, Cohen-Kfir Einav, Yakubovsky Oran, Hallak Noa, Benyamini Hadar, Lishinsky Natan, Offir Neta, Tam Joseph, Dresner-Pollak Rivka
Abstract excerpt
OBJECTIVE: Menopause is associated with visceral adiposity, hepatic steatosis and increased risk for cardiovascular disease. As estrogen replacement therapy is not suitable for all postmenopausal women, a need for alternative therapeutics and biomarkers has emerged. METHODS: 9-week-old C57BL/6 J female mice were subjected to ovariectomy (OVX) or SHAM surgery (n = 10 per group), fed a standard diet and sacrificed...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.