Article
Development of a novel model of cholecystectomy in subsequently ovariectomized mice and characterization of metabolic and gastrointestinal phenotypes: a pilot study.
BMC gastroenterology - 11 Feb 2021
Alexander Celeste, Cross Tzu-Wen L, Lee Anne H, Ly Lindsey K, Vieson Miranda D, Ridlon Jason M, Nelson Erik R, Swanson Kelly S
Abstract excerpt
BACKGROUND: Cholecystectomy (XGB) is the most common abdominal surgery performed in the United States and is associated with an increased post-surgery incidence of metabolic and gastrointestinal (GI) diseases. Two main risk factors for XGB are sex (female) and age (40-50 yr), corresponding with onset of menopause. Post-menopausal estrogen loss alone facilitates metabolic dysfunction, but the effects of XGB on...
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