Article
Associations between APOL1 genetic variants and blood pressure in African American mothers and children from a U.S. pregnancy cohort: Modification by air pollution exposures.
Environmental research - 1 Sept 2022
Ni Yu, Simpson Claire L, Davis Robert L, Szpiro Adam A, Karr Catherine J, Kovesdy Csaba P, Hjorten Rebecca C, Tylavsky Frances A, Bush Nicole R, LeWinn Kaja Z, Winkler Cheryl A, Kopp Jeffrey B, Obi Yoshitsugu
Abstract excerpt
INTRODUCTION: Carriage of high-risk APOL1 genetic variants is associated with increased risks for kidney diseases in people of African descent. Less is known about the variants' associations with blood pressure or potential moderators. METHODS: We investigated these associations in a pregnancy cohort of 556 women and 493 children identified as African American. Participants with two APOL1 risk alleles were...
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