Article
APOL1 renal risk variants are associated with obesity and body composition in African ancestry adults: An observational genotype-phenotype association study.
Medicine - 12 Nov 2021
Nadkarni Girish N, Fei Kezhen, Galarneau Genevieve, Gao Yan, Wilson James G, Cooper Richard, Madden Ebony B, Denny Joshua C, Richardson Lynne D, Pollak Martin, Loos Ruth J F, Horowitz Carol R
Abstract excerpt
ABSTRACT: While increased obesity prevalence among persons of African ancestry (AAs) compared to persons of European ancestry (EAs) is linked to social, environmental and behavioral factors, there are no gene variants that are common and significantly associated with obesity in AA populations. We sought to explore the association between ancestry specific renal risk variants in the apolipoprotein L1 (APOL1) gene...
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