Article
LncRNA SENCR overexpression attenuated the proliferation, migration and phenotypic switching of vascular smooth muscle cells in aortic dissection via the miR-206/myocardin axis.
Nutrition, metabolism, and cardiovascular diseases : NMCD - 1 Jun 2022
Song Yi, Wang Tao, Mu Chunjie, Gui Wenting, Deng Yao, Ma Runwei
Abstract excerpt
BACKGROUND AND AIMS: Smooth muscle and endothelial cell-enriched migration/differentiation-associated lncRNA (SENCR) has been reported to be associated with some cardiovascular diseases; however, its function and exact molecular mechanism in aortic dissection (AD) remain undefined. Thus, we investigated the effects of SENCR on AD and its potential mechanisms. METHODS AND RESULTS: SENCR expression in aortic media...
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