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Article

Model-Based Tacrolimus Follow-up Dosing in Adult Renal Transplant Recipients: A Simulation Trial.

Therapeutic drug monitoring - 1 Oct 2022

Francke Marith I, Hesselink Dennis A, Andrews Louise M, van Gelder Teun, Keizer Ron J, de Winter Brenda C M

Abstract excerpt

BACKGROUND: Initial algorithm-based dosing appears to be effective in predicting tacrolimus dose requirement. However, achieving and maintaining the target concentrations is challenging. Model-based follow-up dosing, which considers patient characteristics and pharmacological data, may further personalize treatment. This study investigated whether model-based follow-up dosing could lead to more accurate...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35344525
DOI: 10.1097/FTD.0000000000000979

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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