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Stathmins and Motor Neuron Diseases: Pathophysiology and Therapeutic Targets

19 Mar 2022

Abstract excerpt

Motor neuron diseases (MNDs) are a group of fatal, neurodegenerative disorders with different etiology, clinical course and presentation, caused by the loss of upper and lower motor neurons (MNs). MNs are highly specialized cells equipped with long, axonal processes; axonal defects are some of the main players underlying the pathogenesis of these disorders. Microtubules are key components of the neuronal...

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PMID: 35327513
DOI: 10.3390/biomedicines10030711

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