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Article

Companion gene mutations and their clinical significance in AML with double or single mutant CEBPA.

International journal of hematology - 1 Jul 2022

He JinYuan, Liu Jie, Shen HongJie, Wang Zheng, Cao LiuJun, Wu Pin, Chao HongYing, Lu XuZhang, Jia ZhuXia, Chen MeiYu, Cai Xiaohui

Abstract excerpt

INTRODUCTION: We report the co-mutations in AML with CEBPAsm or CEBPAdm and their clinical features in a large cohort (n = 302) of CEBPAmut AML patients. MATERIALS AND METHODS: We retrospectively sequenced 112 genes in 302 patients with CEBPAmut using NGS, and studied the spectrum and clinical impact of co-mutations in CEBPAdm and CEBPAsm. RESULTS: ① The average number of mutations in CEBPAsm and CEBPAdm AML was...

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PMID: 35314954
DOI: 10.1007/s12185-022-03322-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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