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Structural insight into African swine fever virus I73R protein reveals it as a Z‐DNA binding protein

21 Mar 2022

Abstract excerpt

African Swine Fever (ASF) is a highly contagious viral haemorrhagic disease of swine, leading to enormous economic losses in the swine industry. However, vaccines and drugs to treat ASF have yet to be developed. African swine fever virus (ASFV) encodes more than 150 proteins, but 50% of them have unknown functions. Here, we present the crystal structure of the ASFV I73R protein at a resolution of 2.0 Å. Similar...

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PMID: 35312168
DOI: 10.1111/tbed.14527

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