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Article

Centenarians as Models of Resistance and Resilience to Alzheimer’s Disease and Related Dementias

1 Jan 2020

Abstract excerpt

The majority of research to understand the pathogenesis of and contributors to Alzheimer's disease (AD) pathology, dementia, and disease progression has focused on studying individuals who have the disease or are at increased risk of having the disease. Yet there may be much to learn from individuals who have a paradoxical decreased risk of AD suggesting underlying protective factors. Centenarians demonstrate...

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PMID: 32743561
DOI: 10.20900/agmr20200018

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