Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Increased expression of Nrf2 and elevated glucose uptake in pheochromocytoma and paraganglioma with SDHB gene mutation.

BMC cancer - 18 Mar 2022

Kamai Takao, Murakami Satoshi, Arai Kyoko, Nishihara Daisaku, Uematsu Toshitaka, Ishida Kazuyuki, Kijima Toshiki

Abstract excerpt

BACKGROUND: Pheochromocytomas (PCC) and paragangliomas (PGL) are catecholamine-producing neuroendocrine tumors. According to the World Health Organization Classification 2017, all PCC/PGL are considered to have malignant potential. There is growing evidence that PCC/PGL represent a metabolic disease that leads to aerobic glycolysis. Cellular energy metabolism involves both transcription factor nuclear factor...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adrenal Gland Neoplasms
Share to Germ-Line Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glucose

Share to NF-E2-Related Factor 2

Share to Paraganglioma

Share to Pheochromocytoma

Share to RNA, Messenger

Share to Succinate Dehydrogenase

Source

Open in PubMed Open full text

Identifiers

PMID: 35300626
DOI: 10.1186/s12885-022-09415-5
PMCID: PMC8931959

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Increased expression of Nrf2 and elevated glucose uptake in pheochromocytoma and paraganglioma with SDHB gene mutation.PMID 35300626Read ↗

The connection between tricarboxylic acid cycle enzyme mutations and pseudohypoxic signaling in pheochromocytoma and paraganglioma.Semantic proximity Read ↗

Genetic and Molecular Biomarkers in Aggressive Pheochromocytomas and Paragangliomas.Semantic proximity Read ↗

Association of Nrf2 expression and mutation with Weiss and Helsinki scores in adrenocortical carcinoma.Semantic proximity Read ↗

Epigenetic and metabolic reprogramming of SDH-deficient paragangliomasSemantic proximity Read ↗

New Insights into the Nuclear Imaging Phenotypes of Cluster 1 Pheochromocytoma and Paraganglioma.Semantic proximity Read ↗

MITOCHONDRIA: Succinate dehydrogenase subunit B-associated phaeochromocytoma and paraganglioma.Semantic proximity Read ↗

Treatment responses to antiangiogenetic therapy and chemotherapy in nonsecreting paraganglioma (PGL4) of urinary bladder with SDHB mutation: A case report.Semantic proximity Read ↗

HIF Signaling Pathway in Pheochromocytoma and Other Neuroendocrine TumorsSemantic proximity Read ↗

Succinate Mediates Tumorigenic Effects via Succinate Receptor 1: Potential for New Targeted Treatment Strategies in Succinate Dehydrogenase Deficient Paragangliomas.Semantic proximity Read ↗

Tumour microenvironment in pheochromocytoma and paragangliomaSemantic proximity Read ↗

Epigenetic and metabolic rewiring in metastatic pheochromocytomas and paragangliomas driven by SDHB mutations.Semantic proximity Read ↗

Genotype-specific abnormalities in mitochondrial function associate with distinct profiles of energy metabolism and catecholamine content in pheochromocytoma and paraganglioma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.