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Article

Association of Nrf2 expression and mutation with Weiss and Helsinki scores in adrenocortical carcinoma.

Cancer science - 1 Jul 2022

Kamai Takao, Murakami Satoshi, Arai Kyoko, Ishida Kazuyuki, Kijima Toshiki

Abstract excerpt

Adrenocortical carcinoma (ACC) is a rare malignant tumor. Genetic abnormalities that may represent therapeutic targets and prognostic factors in ACC remain unclear. Besides being one of the main cellular defense mechanisms that regulates antioxidant pathways for detoxifying reactive oxygen species (ROS), the transcription factor nuclear factor erythroid 2-related factor 2 (Nrf2) promotes tumor proliferation by...

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Identifiers

PMID: 35467062
DOI: 10.1111/cas.15379
PMCID: PMC9277251

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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