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Article

Genetic anticipation of breast cancer among BRCA1/BRCA2 mutation carriers: A retrospective study.

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics - 1 Nov 2022

Kedmi Aviya, Kadouri Luna, Sagy Iftach, Hamburger Tamar, Levin Gabriel, Zimhony-Nissim Noa, Peretz Tamar

Abstract excerpt

OBJECTIVE: To study the anticipation phenomenon among hereditary breast cancer patients, by evaluating trends in age at diagnosis and phenotype of breast cancer across two successive generation pairs of BRCA1/2 mutation carriers/non-carriers with breast cancer after reports of an earlier age of diagnosis in successive generations among BRCA1/2 mutation carrier families. METHOD: A retrospective cohort study....

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Source

Identifiers

PMID: 35278219
DOI: 10.1002/ijgo.14179

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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