Article
Earlier Age of Breast Cancer Onset in Israeli BRCA Carriers-Is it a Real Phenomenon?
The breast journal - 1 Nov 2016
Agranat Sivan, Baris Hagit, Kedar Inbal, Shochat Mordechai, Rizel Shulamith, Perry Shlomit, Margel David, Sulkes Aaron, Yerushalmi Rinat
Abstract excerpt
Data on genetic anticipation in breast cancer are sparse. We sought to evaluate age at diagnosis of breast cancer in daughters with a BRCA mutation and their mothers. A review of all carriers of the BRCA mutation diagnosed with breast cancer at the Genetics Institute of a tertiary medical center in 2000-2013 yielded 80 women who could be paired with a mother with breast cancer who was either a carrier of the BRCA...
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