Article
Anticipation in hereditary breast cancer.
Clinical genetics - 1 Aug 2002
Dagan E, Gershoni-Baruch R
Abstract excerpt
To determine whether familial breast cancer occurs at a younger age in successive generations, we reviewed the clinical records of 435 Ashkenazi women with breast cancer referred to our cancer genetic clinic. Ninety-eight who reported a maternal history of breast cancer were selected for further investigation. All women were genotyped for founder BRCA1/2 mutations (185delAG, 5382insC and 6174delT). Mean age at...
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