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Enhancing the thermostability of transglutaminase from Streptomyces mobaraensis based on the rational design of a disulfide bond.

Protein expression and purification - 1 Aug 2022

Wang Hongjing, Chen Haiqing, Li Qingbin, Yu Fan, Yan Yaru, Liu Shuang, Tian Jian, Tan Jianxin

Abstract excerpt

Transglutaminase (TGase), a transferase, is widely adopted in the food industry and other biological fields due to its unique characteristics of modifying proteins by intra- or intermolecular cross-linking. However, obtaining a mutant TGase that is highly thermostable and active would significantly aid in food processing. Therefore, this study sought to improve the thermostability of TGase by introducing an...

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PMID: 35272012
DOI: 10.1016/j.pep.2022.106079

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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