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Meiotic spindle assembly and chromosome segregation in oocytes

22 Nov 2016

Abstract excerpt

Oocytes accumulate maternal stores (proteins, mRNAs, metabolites, etc.) during their growth in the ovary to support development after fertilization. To preserve this cytoplasmic maternal inheritance, they accomplish the difficult task of partitioning their cytoplasm unequally while dividing their chromosomes equally. Added to this complexity, most oocytes, for reasons still speculative, lack the major microtubule...

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PMID: 27879467
DOI: 10.1083/jcb.201607062

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