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Article

What’s in a Gene? The Outstanding Diversity of MAPT

1 Mar 2022

Abstract excerpt

Tau protein is a microtubule-associated protein encoded by the MAPT gene that carries out a myriad of physiological functions and has been linked to certain pathologies collectively termed tauopathies, including Alzheimer’s disease, frontotemporal dementia, Huntington’s disease, progressive supranuclear palsy, etc. Alternative splicing is a physiological process by which cells generate several transcripts from...

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PMID: 35269461
DOI: 10.3390/cells11050840

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