Article
Exosomal PTEN as a Predictive Marker of Aggressive Gliomas.
Neurology India - 1 Jan 2000
Patnam Sreekanth, Samal Rasmita, Koyyada Rajeswari, Joshi Partha, Singh Anula D, Nagalla Balakrishna, Soma Madan R, Sannareddy Rajesh R, Ippili Kaushal, Raju Subodh, Boola Ratnam G, Lath Rahul, Ranjan Alok, Ghosh Siddharth, Balamurugan M, Ray Amitava, Manda Sasidhar V
Abstract excerpt
Background: Liquid biopsies have emerged as convenient alternative diagnostic methods to invasive biopsies, by evaluating disease-specific biomarkers and monitoring the disease risk noninvasively. Phosphatase and tensin homolog deleted in chromosome 10 (PTEN) is a potent tumor suppressor, and its deletion/mutations are common in gliomas. Objective: Evaluate the feasibility of non-invasive detection of PTEN and...
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