Article
A mixture distribution approach for assessing genetic impact from twin study.
Statistics in medicine - 30 Jun 2022
Hu Zonghui, Li Pengfei, Follmann Dean, Qin Jing
Abstract excerpt
It is challenging to evaluate the genetic impacts on a biologic feature and separate them from environmental impacts. This is usually achieved through twin studies by assessing the collective genetic impact defined by the differential correlation in monozygotic twins vs dizygotic twins. Since the underlying order in a twin, determined by latent genetic factors, is unknown, the observed twin data are unordered....
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