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Article

Modeling extended twin family data I: description of the Cascade model.

Twin research and human genetics : the official journal of the International Society for Twin Studies - 1 Feb 2009

Keller Matthew C, Medland Sarah E, Duncan Laramie E, Hatemi Peter K, Neale Michael C, Maes Hermine H M, Eaves Lindon J

Abstract excerpt

The classical twin design uses data on the variation of and covariation between monozygotic and dizygotic twins to infer underlying genetic and environmental causes of phenotypic variation in the population. By using data from additional relative classes, such as parents, extended twin family designs more comprehensively describe the causes of phenotypic variation. This article introduces an extension of previous...

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Identifiers

PMID: 19210175
DOI: 10.1375/twin.12.1.8
PMCID: PMC4070287

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