Article
A mixture model approach in gene-gene and gene-environmental interactions for binary phenotypes.
Journal of biopharmaceutical statistics - 1 Jan 2008
Li Lang, Yu Menggang, Jason Robarge D, Shen Changyu, Azzouz Faouzi, McLeod Howard L, Borges-Gonzales Silvana, Nguyen Anne, Skaar Todd, Desta Zeruesenay, Sweeney Christopher J, Flockhart David A
Abstract excerpt
In translational research, a genetic association study of a binary outcome has a twofold aim: test whether genetic/environmental variables or their combinations are associated with a clinical phenotype, and determine how those combinations are grouped to predict the phenotype (i.e., which combina...
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