Article
Attributing effects to interactions.
Epidemiology (Cambridge, Mass.) - 1 Sept 2014
VanderWeele Tyler J, Tchetgen Tchetgen Eric J
Abstract excerpt
A framework is presented that allows an investigator to estimate the portion of the effect of one exposure that is attributable to an interaction with a second exposure. We show that when the 2 exposures are statistically independent in distribution, the total effect of one exposure can be decomposed into a conditional effect of that exposure when the second is absent and also a component due to interaction. The...
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