Article
Alternative LIM homeodomain splice variants are dynamically regulated at key developmental steps in vertebrates.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Jul 2022
Wheaton Benjamin Joel, Häggström Sara Lea, Muppavarapu Mridula, González-Castrillón Luz María, Wilson Sara Ivy
Abstract excerpt
BACKGROUND: Alternative splicing provides a broad strategy to amplify the genome. Yet how alternative splicing influences neurodevelopment or indeed which variants are translated at developmental choice points remains poorly explored. Here we focused on a gene important for neurodevelopment, the Lim homeodomain transcription factor, Lhx9. Lhx9 has two noncanonical splice variants, Lhx9a and Lhx9b which compared...
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