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Article

Developmental regulation of gonadotropin-releasing hormone gene expression by the MSX and DLX homeodomain protein families.

The Journal of biological chemistry - 13 May 2005

Givens Marjory L, Rave-Harel Naama, Goonewardena Vinodha D, Kurotani Reiko, Berdy Sara E, Swan Christo H, Rubenstein John L R, Robert Benoit, Mellon Pamela L

Abstract excerpt

Gonadotropin-releasing hormone (GnRH) is the central regulator of the hypothalamic-pituitary-gonadal axis, controlling sexual maturation and fertility in diverse species from fish to humans. GnRH gene expression is limited to a discrete population of neurons that migrate through the nasal region into the hypothalamus during embryonic development. The GnRH regulatory region contains four conserved homeodomain...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 15743757
DOI: 10.1074/jbc.M502004200
PMCID: PMC2932481

Genes

DLX1
MSX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Developmental regulation of gonadotropin-releasing hormone gene expression by the MSX and DLX homeodomain protein families.PMID 15743757Read ↗

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