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Article

Local genetic variation of inflammatory bowel disease in Basque population and its effect in risk prediction.

Scientific reports - 1 Mar 2022

Garcia-Etxebarria Koldo, Merino Olga, Gaite-Reguero Adrián, Rodrigues Pedro M, Herrarte Amaia, Etxart Ane, Ellinghaus David, Alonso-Galan Horacio, Franke Andre, Marigorta Urko M, Bujanda Luis, D'Amato Mauro

Abstract excerpt

Inflammatory bowel disease (IBD) is characterised by chronic inflammation of the gastrointestinal tract. Although its aetiology remains unknown, environmental and genetic factors are involved in its development. Regarding genetics, more than 200 loci have been associated with IBD but the transferability of those signals to the Basque population living in Northern Spain, a population with distinctive genetic...

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Identifiers

PMID: 35232999
DOI: 10.1038/s41598-022-07401-2
PMCID: PMC8888637

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