Article
Immunohistochemical and mutational status of telomerase reverse transcriptase in conjunctival squamous cell carcinoma.
Indian journal of ophthalmology - 1 Mar 2022
Jayaraj Perumal, Sen Seema, Saxena Kartikey, Gupta Jassika, Vats Pranjal, Kashyap Seema, Chauhan Sheetal, Pushker Neelam
Abstract excerpt
PURPOSE: Mutations in human telomerase reverse transcriptase (TERT) are associated with increased telomerase activity in cutaneous melanomas. Conjunctival squamous cell carcinoma, also referred to as ocular surface squamous cell carcinoma, is cancer on the surface of the eye. Recent studies have identified UV signat`ure mutations in TERT promoters in ocular melanoma and ocular surface squamous neoplasia. However,...
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