Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Detection of HBV Covalently Closed Circular DNA

6 Jun 2017

Abstract excerpt

Chronic hepatitis B virus (HBV) infection affects approximately 240 million people worldwide and remains a serious public health concern because its complete cure is impossible with current treatments. Covalently closed circular DNA (cccDNA) in the nucleus of infected cells cannot be eliminated by present therapeutics and may result in persistence and relapse. Drug development targeting cccDNA formation and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hepatitis B Virus Studies
Share to Hepatitis C virus research
Share to Pancreatic and Hepatic Oncology Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28587292
DOI: 10.3390/v9060139

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Detection of HBV Covalently Closed Circular DNAPMID 28587292Read ↗

Approaches to quantifying hepatitis B virus covalently closed circular DNASemantic proximity Read ↗

Clinical relevance of the study of hepatitis B virus covalently closed circular DNASemantic proximity Read ↗

Research progress in hepatitis B virus covalently closed circular DNASemantic proximity Read ↗

Targeting the Achilles heel of the hepatitis B virus: a review of current treatments against covalently closed circular DNA.Semantic proximity Read ↗

Role of hepatitis B virus in development of hepatocellular carcinoma: Focus on covalently closed circular DNASemantic proximity Read ↗

Mapping the Interactions of HBV cccDNA with Host FactorsSemantic proximity Read ↗

HBV cccDNA─A Culprit and Stumbling Block for the Hepatitis B Virus Infection: Its Presence in Hepatocytes Perplexed the Possible Mission for a Functional CureSemantic proximity Read ↗

A novel method to precisely quantify hepatitis B virus covalently closed circular (ccc)DNA formation and maintenanceSemantic proximity Read ↗

Current Status and Challenges in Anti-Hepatitis B Virus Agents Based on Inactivation/Inhibition or Elimination of Hepatitis B Virus Covalently Closed Circular DNASemantic proximity Read ↗

Insights for clinical diagnostic indicators of virus and host in chronic hepatitis B infectionSemantic proximity Read ↗

Functional cure of hepatitis B requires silencing covalently closed circular and integrated hepatitis B virus DNASemantic proximity Read ↗

Epigenetic regulation of hepatitis B virus covalently closed circular DNA: Implications for epigenetic therapy against chronic hepatitis BSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.