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Article

Assessment of causal effects of visceral adipose tissue on risk of cancers: a Mendelian randomization study.

International journal of epidemiology - 10 Aug 2022

Lu Yao, Tang Haibo, Huang Peiyuan, Wang Jie, Deng Peizhi, Li Yalan, Zheng Jie, Weng Liang

Abstract excerpt

BACKGROUND: Despite the established association between obesity and cancer risk, it remains unclear whether visceral obesity is causally related to cancer risk and whether it is more pro-oncogenic than total body fat. METHODS: We conducted two-sample Mendelian randomization (MR) analysis to assess the causal effects of visceral adipose tissue (VAT) on six common cancers. For exposure data, 221 genetic variants...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35218345
DOI: 10.1093/ije/dyac025
PMCID: PMC9380424

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