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Causal associations between liver traits and Colorectal cancer: a Mendelian randomization study

6 Dec 2023

Abstract excerpt

OBJECTIVE: This study aimed to investigate the causal associations between several liver traits (liver iron content, percent liver fat, alanine transaminase levels, and liver volume) and colorectal cancer (CRC) risk using a Mendelian randomization (MR) approach to improve our understanding of the disease and its management. METHODS: Genetic variants were used as instrumental variables, extracted from genome-wide...

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PMID: 38057864
DOI: 10.1186/s12920-023-01755-w

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